Alzheimer related information

Two projects for the confidence of the foundation of partnership NHS of Sul Essex (SEPT) to promote the dignity and independence for the peoples who suffer from the dementia had been praised highly in this year east of the health of England and the social concessions of the care.

The innovative durable memories of the projects ‘ and ‘ my history of the life ‘ had been launched in December 2007 and work prxima with patients, its carers, families and friends to improve its quality of life.
‘ the durable memories are specifically the aimed at patients and its carers that they have been diagnosised recently with dementia. The project allows that the patients make examination of the control of its care and choose the services that receive, together with starting the information on its condition in the advanced periods of training.

‘ the project of the my history of the life ‘ is a book personalized of the life of the patients with dedicated sections including my advanced years, my life of the adult and all on me. The users of service, carers and the team of employees work together to create an accurate register of the life of a person who includes anecdotes, photographs and the useful information such as the food and the preferences of the drink.

Dr. Patrick Geoghegan OBE, main executive, said: “make projects as these a real difference not only our users of service, but its carers too much. I am delighted that they had been praised in this year east of the health of England and the social concessions of the care. It is also a demonstration of all the hard work that our team of employees makes and is fantastic that this estve recognized “.

Other projects to reach the ends of the health and the social concessions of the care include ‘ the road to the recovery ‘ and ‘ the care connecting with the partnership ‘.

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A game of molecules found in determined plants seems to have a beneficial effect in the fabric of the brain associated with the illness of Alzheimer, in accordance with a lead new study in the rats. The study it was lead by investigators in the university of the south medical center of Flowery and Cedro-Cedars-Sinai. An article in the periodical of the cellular and molecular medicine is in available line.

The city of Terrence, Ph.D., one of the senior authors of the study, is available to supply more information on this study. She is a scientist of research with the departments of neurosurgery and of sciences biomedical in the medical center of Cedro-Cedars-Sinai, and with the center of neurosurgical research of the hospital, neurosurgical institute of Maxine Dunitz.

The investigators had managed molecules called flavonoids, that they are found in determined fruits and vegetables, to a model the programmed rat genetically to develop the illness of Alzheimer. Using two of these molecules, luteolin and diosmin, they could reduce the levels of a called protein amyloid-amyloid-beta, that of this form to the sticky deposits that construct above in the brains of the patients with Alzheimer. The investigators had also determined that these molecules work whitening a called protein presenilin-1, that has been on for much time the Alzheimer as a cause genetic of this illness devastating and untreatable.

The results can offer a new approach to the therapy for the patients who suffer from this illness neurodegenerative, that it is the most common cause of the dementia and is esteem to affect five million more than peoples in the United States.

“these flavonoids are extensively available in natural foods and seem that therapeutic can be used in the form purified as agents. The composites have few if all the side effects and are natural in citrus fruits. Also they can be found as dietary supplements in store of the health food, “said city.

Tan June, M.D., Ph.D., with the university of the south department of Flowery of psychiatry, dirige the study. Other authors are: Kavon Rezai-Zadeh (first author), R. Douglas Shytle, Ph.D., Yun Bai, M.D., Ph.D., Tian June, M.D., Ph.D., Huayan Hou, M.D., Ph.D., Takashi Mori, D.V.M., Ph.D., Jin Zeng, M.D., and Demian Obregon.

The study it was supported by the national justinian codes of the health and by the institute of the center & of research of the Alzheimer of Mr. of Johnnie B. Byrd.

Citation: The periodical of the cellular and molecular medicine, “phosphorylation presenilin-1 Flavonoid-mediated reduces the production do?-?-amyloid of the illness of Alzheimer,” April in published line 17, 2008

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Obesity can increase the risk of the adults to have the dementia, in accordance with investigating in the school of Johns Hopkins Bloomberg of the public health. Its analysis of studies of perspective continuation published of obesity and the dementia on the two last samples of the decades a consistent relationship between the two illnesses. The results are published by the international association for the study of obesity in the May, introduction 2008 of revisions of obesity.

“our analysis of the data shows to an association clear between obesity and a risk increased for the diverse dementia and subtypes physicians of the illness,” said Youfa Wang, MD, PhD, senior author of the study and professor of associate with the center of the school of Bloomberg for nutrition human. the “subjects with a healthful circumference of the index (BMI) and the waist of the mass of the body turn a risk diminished for the dementia of that its counterparts with a circumference elevated of BMI or waist.” Wang adds, “to hinder or to treat obesity in a new age they could play a main paper in generally reducing the number of patients and those of the dementia with other illnesses associates such as the illness of Alzheimer for up to 20 percent in the United States.”

The Beydoun, together leads to the investigating May with the attribute of Wang and H.A. Beydoun these findings to a systematic revision of 10 studies previously published that they had examined the relationships between the dementia or its measures of subtypes and the several of the body fat. Based in an analysis pooled of its findings of 7 of the studies, obesity of the comparative line of base to the normal weight increased the risk of the illness of Alzheimer for 80 percent in the average. Additional of the concldo team that to be underweight also increases the risk of the dementia and its subtypes. The studies cited in the goal-analysis had been lead in a number of countries, including the states, the joined Finland, Sweden and the France, and had contained older adults middle-aged and.

The research previously published defines the dementia as an only one not disorder, but a number of syndromes characterized by impairments behavioral, cognitive, and emotional diverse. The most common form is illness of Alzheimer, with the 5 million adult esteem that lives with the illness in the United States alone.

“currently, the illness of Alzheimer is the eighth root cause of the death enters the aged population in the United States. When more studies will be needed to determine the optimal weight and the biological mechanisms associates with obesity and the dementia, these findings could potential diminish the number of the peoples diagnosised with dementia and to lead to a quality of more good total life, “said May the Beydoun, previous a postdoctoral friend of the research in the school of Johns Hopkins Bloomberg of the public health.

“obesity and obesity central as factors of risk for the dementia of incident and its subtypes: a systematic revision and an goal-analysis “had been written by M. Beydoun, H. Beydoun and Y. Wang.

The research was financed by the school of Johns Hopkins Bloomberg of the public health.

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